Skip to main content

Human T-Cadherin(30K, 130K) ELISA

$891.00
SKU:
27365
Adding to cart… The item has been added

Solid phase sandwich ELISA designed for the determination of T-Cadherin (30k, 130k) in human serum and EDTA-plasma. For research use only, not for use in diagnostic procedures. <br><br>

T-Cadherin is a protein that binds to Adiponectin (APN), an adipocyte-secreted factor.
APN binds to and accumulates in aorta, heart, skeletal muscle, and mesenchymal stem cells in systemic tissues via T-Cadherin, and is thought to promote exosome production and exert a protective effect on organ tissues. In addition, SNPs near the T-Cadherin gene are strongly associated with glucose intolerance and cardiovascular disease risk in humans.<br><br>

Recently, it was reported that soluble T-Cadherin exists in human blood in three forms: 130kDa, 100kDa, and 30kDa. These three soluble forms of T-Cadherin correlate with various clinical parameters in patients with type 2 diabetes, and their concentrations change rapidly in the acute phase of myocardial infarction, so they are expected to be useful as biomarkers.

In addition, soluble T-Cadherin has been found to promote the proliferation of pancreatic beta cells and inhibit the decline in insulin secretory capacity, and its function as a humoral factor is also in focus.<br><br>

We provide 3 ELISA kits that measure (1) 130kDa molecular species only, (2) 30kDa + 130kDa molecular species, and (3) 100kDa + 130kDa molecular species.

Assay Description:
90 min. (37°C) + 30 min. (2-8°C) + 30 min. (RT) = 2 hours total incubation time
Catalog number:
27365
Configuration:
96 Determinations, 12x8 removable strips
Controls:
None provided
Design:
Solid phase sandwich ELISA
FDA Status:
For research use only, not for use in diagnostic procedures
MSDS:
Please inquire
Protocol:

Protocol

Notes:
The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
Sample types:
Human Serum, EDTA-plasma
Sample volume:
100 uL of properly diluted unknown / determination
Standards:
7 standards, serially diluted from 1 prepared lyophilized standard
Standard Range:
0/ 0.02 - 1.5 ng/mL
Storage:
2 - 8 °C
Sensitivity:
0.005 ng/mL
Species:
Human
Pamphlets:

Human T-Cadherin (30K, 130K)