Nephrology is the branch of medicine and research that deals with the physiology and diseases of the kidneys.
Modern definitions of CKD and AKI emphasize a stage of decreased glomerular filtration rate (GFR), and a stage of kidney damage, defined as structural or functional abnormalities before a decline in GFR.
The one-dimensional standard of kidney disease detection is incompatible with the complexity of renal pathology. The diagnosis of kidney disease has largely focused on glomerular filtration, while assessment of kidney tubular health has notably been absent. Kidney tubular cells undergo a cascade of cellular responses that result in the production and accumulation of low-molecular-weight proteins in the urine and systemic circulation. Recent advancements in molecular analysis and proteomics have allowed the identification and quantification of these proteins as biomarkers for researching and characterizing kidney diseases.
This category is comprised of unique biomarker ELISA kits that support research in the broad spectrum of acute to chronic kidney diseases.