Blog
Publication Spotlight: The C99 domain of the amyloid precursor protein resides in the disordered membrane phase.
Jun 21st 2022
Capone R, Tiwari A, Hadziselimovic A, Peskova Y, Hutchison JM, Sanders CR, Kenworthy AK. The C99 domain of the amyloid precursor protein resides in the disordered membrane phase. J Biol Chem. 2021 Jan …
N3pE Amyloid-beta Isoform Assays
Jun 26th 2019
Amyloid-beta is generated through amyloid precursor protein (APP) cleavage by specific secretases. Beta-secretase cleaves an extracellular portion of APP and frees a soluble peptide. Gamma-secr …