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Amyloid Beta / APP Research Kits and Antibodies

Alzheimer's disease is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NTFs) in the brain.

Amyloid Beta is a peptide derived from the amyloid precursor protein (APP), which is cleaved by beta secretase and gamma secretase to yield Aβ. Aβ is the main component of Amyloid plaques, which are insoluble clumps of beta proteins that are potentially toxic to neurons and their synapses.

Research suggests that the plaques disrupt communication between brain cells, which would result in cognitive decline.

The Tau protein is a microtubule-associated protein which stabilizes the microtubules that transport intracellular substances in nerve cells. When Tau malfunctions, it detaches from these microtubules and sticks to other Tau molecules, where threads are formed. These threads eventually result in neurofibrillary tangle.

Since Tau is interfering with intraneuronal transport and metabolism during this process, research suggests this plays another major role in cognitive decline.

In addition to a complete selection of research assays for the various Amyloid beta molecules, IBL-America also offers antibodies and test kits targeting Tau protein, APPα and β, as well as other significant molecules.

  • Item
    Size/Catalog #
    Species
    price
  • 27713
    Online Store
    $587.00
  • 27719
    Online Store
    $740.00
  • 27721
    Online Store
    $740.00
  • 27711
    Online Store
    $627.00
  • 27710
    Online Store
    $709.00
  • 27729
    Online Store
    $587.00
  • 27725
    Online Store
    $765.00
  • 10323
    Online Store
    $509.00
  • 10326
    Online Store
    $509.00
  • 18584
    Online Store
    $509.00
  • 10045
    Online Store
    $509.00
  • 27716
    Online Store
    $490.00

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