Polyclonal Antibodies

Polyclonal antibodies (pAbs) are a combination of antibodies, derived from the immune response of multiple B-cells, and each one recognizes a different epitope on the same antigen.

Polyclonals are produced by injecting an animal with an antigen. This elicits the immune response that produces antibodies against that antigen. The polyclonal immunoglobulins are then purified from the animal’s blood serum.

IBL-America offers a wide range of polyclonal antibodies that can be used in research using multiple laboratory testing methods.

COX-1 (C24) Anti-Human Rabbit IgG Affinity Purify 1

COX-1 and COX-2 (Cyclooxygenase 1,2) are also called prostaglandin endoperoxide H synthase, and are important enzymes as catalysts for the reaction in prostaglandin H2 (PGH2) synthesis from the arachidonic acid. COX-1 and COX-2 have the homology of about...

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c-Met β Anti-Human Rabbit IgG Affinity Purify 1

Overexpression of the hepatocyte growth factor receptor (c-Met/HGF receptor), a transmembrane tyrosine kinase encoded by the MET proto-oncogene, is involved in transformation and invasive behavior of human carcinomas and sarcomas. For research use...

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Claudin-7 (C) Anti-Murine Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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Claudin-6 (C) Anti-Mouse Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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Claudin-15 (C) Anti-Mouse Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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Claudin-12 (C) Anti-Mouse Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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Claudin-1 (C) Anti-Murine Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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Anti-c-Kit (K963) Rabbit IgG Affinity Purify 1

The proto-oncogene c-kit encodes a transmembrane tyrosine kinase receptor, and its ligand for c-Kit receptor has been identified as the stem cell factor (SCF). Recent experimental studies have shown that c-Kit plays a key role in the development of a...

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C-ERC/Mesothelin (306) Anti-Rat Rabbit Igg Affinity Purify 1

Erc has been identified as a gene showing stronger expression in cancer-affected renal cell than in normal renal tissue in Eker rats (a rat model of renal cancer). The human homologue of the protein encoded by this gene is called MPF (megakaryocyte...

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CD109 (1383) Anti-Human Rabbit IgG Affinity Purify 1

CD109 is a glycosyl-phosphatidyl-inositol (GPI) - anchored glycoprotein about 180 - 190 kDa. It is shown that CD109 is expressed in vascular endothelial cells, some epithelial cells, activated T-cells and platelets, and subset of CD34+ megakaryocytic...

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Big Endothelin-1 (22-38) Anti-Human Rabbit IgG Affinity Purify 1

Endothelins are 21 amino acid peptides that are produced ubiquitously by vascular endothelial cells, smooth muscle cells, and other cells in different organs. Endothelins are secreted as big-endothelins that are converted to active proteins by the...

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Anti-BACE1 (42) Rabbit IgG Affinity Purify 1

The current understanding of the role of amyloid in Alzheimer's disease (AD) has been established by a remarkable congruence of multiple disciplines: neuropathology, biochemistry, molecular biology, and epidemiological genetics. It is known that...

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