Polyclonal Antibodies

Polyclonal antibodies (pAbs) are a combination of antibodies, derived from the immune response of multiple B-cells, and each one recognizes a different epitope on the same antigen.

Polyclonals are produced by injecting an animal with an antigen. This elicits the immune response that produces antibodies against that antigen. The polyclonal immunoglobulins are then purified from the animal’s blood serum.

IBL-America offers a wide range of polyclonal antibodies that can be used in research using multiple laboratory testing methods.

TNF-α Anti-Rat Rabbit IgG Affinity Purify 1

TNF-α (Tumor Necrosis Factor alpha) is a 17.5 kDa, 157 amino acid protein that is a potent lymphoid factor, which exerts cytotoxic effects on a wide range of tumor cells and other target cells. TNF-α has been suggested to play a...

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Tie (N1125) Anti-Human Rabbit IgG Affinity Purify 1

TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...

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α-Synuclein (S122) Anti-Human Rabbit IgG Affinity Purify 1

The pre-synaptic protein, α-synuclein, has been associated with the pathogenesis of several neurodegenerative diseases. These include prevalent conditions such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and the Lewy body variant...

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Syndecan-4 Anti-Human Rabbit IgG Affinity Purify 1

Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular...

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Anti-Smad3C (Ser 423/425 Phosphorylated) Rabbit IgG Affinity Purify 1

Smads are critical mediators conveying signals from the TGF-β-superfamily members to the nucleus. Activated TGF-β type I receptor (TβRI) and c-Jun N-terminal kinase (JNK) differentially phosphorylate Smad3 to convert two distinctive...

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Sir2/SIRT1 Anti-Human Rabbit IgG Affinity Purify 1

Imai et al. have found that S. cerevisiae Sir2p and its higher eukaryotic orthologs are novel nicotinamide adenine dinucleotide (NAD)-dependent histone/protein deacetylases. Sir2 proteins promote longevity in yeast and in C. elegans by silencing rDNA and...

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Septin 4 (N) Anti-Human Rabbit IgG Affinity Purify 1

A cytoskeletal or scaffold protein family named “septin” has been shown to be involved in diverse phenomena in the living body, including cell division. The term “septin” is derived from “septation,” which means...

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Anti-SCF (K236) Rabbit IgG Affinity Purify 1

Stem cell factor (SCF) and its receptor KIT play an important role in various biologic phases, such as hematopoiesis, reproduction, and regeneration.　 Structurally, c-Kit contains five immunoglobulin-like domains extracellularly and a catalytic domain...

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Anti-SCF (K165) Rabbit IgG Affinity Purify 1

Stem cell factor (SCF) and its receptor KIT play an important role in various biologic phases, such as hematopoiesis, reproduction, and regeneration. Structurally, c-Kit contains five immunoglobulin-like domains extracellularly and a catalytic domain...

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Anti-SCF (K089) Rabbit IgG Affinity Purify 1

Stem cell factor (SCF) and its receptor KIT play an important role in various biologic phases, such as hematopoiesis, reproduction, and regeneration.　 Structurally, c-Kit contains five immunoglobulin-like domains extracellularly and a catalytic domain...

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RON (G1385) Anti-Human Rabbit IgG Affinity Purify 1

The c-MET gene encodes the tyrosine kinase p190MET, the receptor for a molecule known as Scatter Factor (SF) or Hepatocyte Growth Factor (HGF). This molecule has biological activities on epithelial sheets, including mitogenesis, cell-cell dissociation,...

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Rictor (R1291) Anti-Human Rabbit IgG Affinity Purify 1

Rictor (rapamycin-insensitive companion of mTOR/ mAVO3) is about 200 kDa and identified as an mTOR-binding protein. Rictor is a factor that constitutes a complex with mLST8 and Sin 1 which is called mTORC2 (mTOR complex 2), and it is contrasted with...

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