LRG (128) Anti-Rat Rabbit Affinity Purify

Among the diseases which should be distinguished from iNPH (idiopathic normal pressure hydrocephalus) of elderly people showing symptoms such as gait disorder and dementia, there are some neurodegenerative diseases such as Alzheimer's disease, FTLD (frontotemporal lobar degeneration) and disorder associated with Parkinson's disease. iNPH can be treated by ventriculo-peritoneal shunt (VP shunt), so a marker in spinal fluid which can distinguish it from neurodegenerative diseases in an early stage has been required. Arai, Miyajima et al. had identified the high level of leucine-rich alpha-2-glycoprotein (LRG) in cerebrospinal fluid of iNPH patients, and they reported that measurement of LRG would be useful for differential identification of iNPH. This antibody shows positive signals with choroids plexus cells and cilia of ependymal cells of rat. For research use only, not for use in diagnostic procedures.