Human CTSD (Cathepsin D) ELISA
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Enzyme immunoassay for detection of CTSD concentrations in serum, plasma, cell culture supernatant and other biological samples. For research use only. Not for use in diagnostic procedures.
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins . It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D may also be secreted into the cytosol during apoptosis and contribute to cleavage of substrates implicated in the apoptotic pathway.
Enzyme immunoassay for detection of CTSD concentrations in serum, plasma, cell culture supernatant and other biological samples. For research use only. Not for use in diagnostic procedures.
Cathepsin D is a ubiquitously expressed lysosomal aspartyl protease involved in the normal degradation of proteins . It is synthesized as an inactive 43 kDa preprocathepsin D that is cleaved and glycosylated to form a 46 kDa procathepsin D and then further cleaved to produce 28 kDa and 15 kDa subunits (heavy and light chains, respectively). Cathepsin D may also be secreted into the cytosol during apoptosis and contribute to cleavage of substrates implicated in the apoptotic pathway.