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Antibodies

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An antibody is an immunoglobulin protein capable of specific combination with an antigen/hapten that has elicited and induced an immune response. Antibodies are produced by B cells in response to presence of antigen/hapten.

  • Tie-1 (9C1) Anti-Human Mouse IgG MoAb

    Tie-1 (9C1) Anti-Human Mouse IgG MoAb

    TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...

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  • PDGFRβ (22B1) Anti-Human Mouse IgG MoAb

    PDGFRβ (22B1) Anti-Human Mouse IgG MoAb

    PDGF, a ligand of PDGFR, has 4 isofoms, A-, B-, C- and D-chains, and forms hetero and/or homo dimers, PDGF-AA, -AB, -BB, -CC, -DD. On the other hand, PDGFR has 2 isoforms, α- and β-chains and forms hetero and/or homo dimers,...

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  • KDR (23B31) Anti-Human Mouse IgG MoAb

    KDR (23B31) Anti-Human Mouse IgG MoAb

    KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed...

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  • CD20 (N) (4-6H:2C) Anti-Human Mouse IgG MoAb

    CD20 (N) (4-6H:2C) Anti-Human Mouse IgG MoAb

    Rituximab used for treatment of lymphoma is an antibody drug of which target is pan-B cell marker, CD20. It has been reported that the C-terminal region of CD20 undertakes a critical role in a binding to rituximab and the association between C-terminal...

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  • BEC12 (LA5) Anti-Mouse Mouse IgG MoAb

    BEC12 (LA5) Anti-Mouse Mouse IgG MoAb

    Recent years, specific antigens of vascular endothelium have been found one after another, and they contribute to progress of vascular biology. This antibody, being unlike any other prior antibodies, reacts especially with arterial microcirculating...

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  • LEC26 (LA102) Anti-Mouse Rat IgG MoAb

    LEC26 (LA102) Anti-Mouse Rat IgG MoAb

    Recent years, LYVE-1 (1999, Banerji et al.), podoplanin (1999, Breiteneder-Geleff et al.) and Prox-1 (1999, Wifle & Oliver) were found one after another as specific antigens of lymphatic endothelium and the approach to lymphatic study has progressed...

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  • Anti-CD25 (H-8) Mouse IgG MoAb

    Anti-CD25 (H-8) Mouse IgG MoAb

    CD25 is IL-2 receptor α chain (IL-2Rα which is a low-affinity receptor of IL-2. CD25 forms high-affinity IL-2 receptors associating with CD122 (β chain) and CD132 (γc chain). CD25 is expressed in activated T cells and B cells...

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  • Anti-CD25 (H-48) Mouse IgG MoAb

    Anti-CD25 (H-48) Mouse IgG MoAb

    CD25 is IL-2 receptor α chain (IL-2Rα which is a low-affinity receptor of IL-2. CD25 forms high-affinity IL-2 receptors associating with CD122 (β chain) and CD132 (γc chain). CD25 is expressed in activated T cells and B cells...

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  • CyCAP (74) Anti-Rat Rabbit IgG Affinity Purify

    CyCAP (74) Anti-Rat Rabbit IgG Affinity Purify

    CyCAP is a binding protein for cyclophilin C in competition with cyclosporine. It is present in brain, kidney and macrophage cells and is known as an inflammation-related protein. In recent years, it has been reported that CyCAP forms complexes with...

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  • CD109 (641) Anti-Human Rabbit IgG Affinity Purify

    CD109 (641) Anti-Human Rabbit IgG Affinity Purify

    CD109 is a glycosyl-phosphatidyl-inositol (GPI) - anchored glycoprotein about 180 - 190 kDa. It is shown that CD109 is expressed in vascular endothelial cells, some epithelial cells, activated T-cells and platelets, and subset of CD34+ megakaryocytic...

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  • Tti1/KIAA0406 Anti-Human Rabbit IgG Affinity Purify

    Tti1/KIAA0406 Anti-Human Rabbit IgG Affinity Purify

    Mammalian target of rapamycin (mTOR), a member of the phosphatidylinositol 3-kinase-related kinase (PIKK), is a major regulator of translation, cell growth, and autophagy. mTOR constitutes two distinct complexes, mTORC1 and mTORC2, that differ in their...

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