Solid phase sandwich enzyme-linked immunosorbent assay (ELISA) for the determination of HCP (Host Cell Protein) originated from cell culture medium using Corynex® System*. <br><br>
CORYNEX® is a novel protein/peptide expression system using Corynebacterium glutamicum (Corynebacterium Expression System). In the CORYNEX® system, C. glutamicum synthesizes and secretes recombinantly expressed proteins/peptides directly into the extracellular fermentation broth. Properly folded recombinant proteins can be recovered from the broth, which eliminates the processes of cell lysis and refolding. In the CORYNEX® system, host protein secretion has been minimized, and recombinant proteins may be transported extracellularly via one of two secretory pathways. Because C. glutamicum is a gram-positive bacterium, it lacks endotoxins, which simplifies the purification process. The CORYNEX® system has the advantage of a scalable, high cell-density fermentation process that can be used to manufacture commercially valuable proteins such as biopharmaceuticals, drug targets, and enzymes.<br><br>
This product is a complete ELISA kit for the quantitative determination of the host cell proteins derived from CORYNEX® culture broth, using rabbit antibodies.
The kit is for Research and Manufacturing Use Only and is not intended for diagnostic use in humans or animals.