Oligodendorocytes are defined as the glial cells of the central nervous system that make and maintain myelin wrapping around a nerve cell axon. And further, oligodendrocytes are considered as target of some disease such as autoimmune disease and brain tumor. However, there are some problems such that the antibody to oligodendrocytes using in immunostaining has low stability and hardly react oligodendroglioma as tumor of oligodendrocytes. Olig2 is a transcription factor that controls development and differentiation of oligodendrocytes. It is reported that human Olig2 is specifically expressed in both oligodendrocytes and oligodendroglioma. For research use only, not for use in diagnostic procedures.