MBD3 (Methyl-CpG-Binding Protein 3) (3A3) Anti-Human Mouse IgG MoAb

Methylation at CpG dinucleotides in genomic DNA is a fundamental epigenetic mechanism of gene expression control in vertebrates. Proteins with a methyl-CpG binding domain (MBD) can bind to single methylated CpGs and most of them are involved in transcription control. So far, five vertebrate MBD proteins have been described as MBD family members: BD1, MBD2, MBD3, MBD4 and MECP2. For research use only, not for use in diagnostic procedures.