KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed that they play important roles in the signal transduction of endothelial and lymphatic endothelial cells. It is understood that after binding with VEGF, Flt-1 and KDR/Flk-1 stimulate the vascular endothelial cells in a coordinated action. For research use only, not for use in diagnostic procedures.