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In signal transduction system, IκB acts as inhibitor to forms complex with NF-κB in cytoplasm and subsequently to inactivate NF-κB. NF-κB is transcription factor distributed in various cells. NF-κB is considered to control various gene expression by degradation of IκB and subsequent translocation of degradation products to nuclear in accordance with various stimulation. For research use only, not for use in diagnostic procedures.
In signal transduction system, IκB acts as inhibitor to forms complex with NF-κB in cytoplasm and subsequently to inactivate NF-κB. NF-κB is transcription factor distributed in various cells. NF-κB is considered to control various gene expression by degradation of IκB and subsequent translocation of degradation products to nuclear in accordance with various stimulation. For research use only, not for use in diagnostic procedures.