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hnRNP (heterogenous nuclear ribonucleoprotein) is a nuclear RNA binding protein and its family consists of about 30 polypeptides. It plays a role in the splicing of pre-mRNA into the mature product in association with small nuclear ribonucleoprotein (snRNP) and splicing factors. The hnRNP B1 was recently shown to be up-regulated in the early stage of lung cancer. Over-expression of hnRNP has been suggested as evidence that normal transcriptional regulation is altered. For research use only, not for use in diagnostic procedures.
hnRNP (heterogenous nuclear ribonucleoprotein) is a nuclear RNA binding protein and its family consists of about 30 polypeptides. It plays a role in the splicing of pre-mRNA into the mature product in association with small nuclear ribonucleoprotein (snRNP) and splicing factors. The hnRNP B1 was recently shown to be up-regulated in the early stage of lung cancer. Over-expression of hnRNP has been suggested as evidence that normal transcriptional regulation is altered. For research use only, not for use in diagnostic procedures.