Cluster of differentiation 57 (CD57), also known as NK-1, is an antigen detectable in natural killer cells, some T-lymphocytes and normal peripheral blood mononuclear cells, myeloid cells, and a variety of polypeptides, lipids, and chondroitin sulfate proteoglycans. CD57 is indicated as a marker for tumors of neuroendocrine origin, including pheochromocytomas, paragangliomas, carcinoid tumor, and medulloblastomas, as well as various neural tumors including neuromas, neurofibromas, schwannomas, and granular cell tumors. CD57 is also detectable in ganglioneuroma and prostate carcinoma. Anti-CD57 is used to distinguish nodular lymphocyte-predominant Hodgkin’s lymphoma from T-cell/histiocyte-rich large B-cell lymphoma, nodular sclerosis Hodgkin’s disease, and follicular lymphoma.
- application:
- IHC
- Catalog number:
- IHC539-1
- clone:
- IHC539
- concentration:
- N/A
- Datasheet:
- formulation:
- Tris Buffer, pH 7.3 - 7.7, with 1% BSA and <0.1% Sodium Azide
- immunogen:
- Recombinant Human CD57
- isotype:
- IgM
- MSDS:
- N/A
- notes:
- For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details. - Other names:
- N/A
- Protocol:
- N/A
- size:
- 1.0 mL
- storage:
- 2-8°C (Do not freeze).
- Species:
- Human
- Host:
- Mouse