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Reticulocalbin-1 (TMU-6A1) Anti-Human Mouse IgG MoAb
Human Reticulocalbin-1 is a 44kDa protein and belongs to the EF (elongation factor) -hand calcium-binding protein family, and it is known as a luminal protein of endoplasmic reticulum (ER) with the C-terminal HDEL (ER retention signal) sequence. Although...
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RIG-I (CTD) Anti-Human Rabbit IgG Affinity Purify
RIG-I (retinoic acid inducible gene-I) is one of cytoplasmic viral sencers which has a RNA helicase domain and it is believed to recognize virus-derived double-stranded RNA (dsRNA). It is considered that RIG-I normally exist as inactive form in cytoplasm...
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c-MPL/TPOR (AMM2) Anti-Mouse Rat IgG MoAb
Thrombopoietin promotes the growth and differentiation (proliferation) of megakaryocytes which produce platelets. TPOR (Thrombopoietin receptor), which is also called c-MPL (Myeloproliferative leukemia protein) or CD110, is a receptor for thrombopoietin...
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ALK (mAb 16-39) Anti-Mouse Rat IgG MoAb
Anaplastic lymphoma kinase (ALK, anaplastic lymphoma kinase) is a receptor type tyrosine kinase, and is found to be expressed in the central and peripheral nervous system at late embryonic stage. Motegi et al. developed an agonist monoclonal antibody...
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Anti-Poly (ADP-ribose) (10H) Mouse IgG MoAb
The poly ADP-ribosylation is one of post translational modification of proteins, and is the addition of many ADP-ribose moieties to a protein. This protein modification is carried out by the poly ADP-ribose polymerases (PARPs), which are found in most...
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Anti-Smad2L/3L (T220/T179 Phosphorylated) (1A1) Mouse IgG MoAb
Phosphorylation of signal transduction molecules, Smad2 and Smad3, can be an important information for understanding of various biological functions of transforming growth factor (TGF)-β. TGF-β type I receptor and cyclin-dependent kinases...
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IRF-3 (S386 Phosphorylated) Anti-Human Rabbit IgG Affinity Purify
Interferon Regulatory Factor-3 (IRF-3) is the gene coding for a regulatory factor that mediates the action of IL-1, TNFα and LPS. It is reported that IRF-3 controls the production of interferons and chemokines in virus infected cells, by a...
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Tau Anti-Human Rabbit IgG Affinity Purify
Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50-70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. It is known that six isoforms of tau protein formed by...
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Nestin (N1602) Anti-Human Rabbit IgG Affinity Purify
Nestin is one of the intermediate filaments abundantly produced in the developing central nervous system and sometimes in the embryonic stage. Nestin is also reportedly detected in gliomas/glioblastomas. Thus, the antibody against nestin can be widely...
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Nephrin (C) Anti-Human Rabbit IgG Affinity Purify
The kidney is an important organ that maintains a homeostasis of body-fluid and nutrition. The capillary walls of renal glomeruli allow the efficient removal of the metabolic waste (filter) and conservation of essential circulating proteins, such as...
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LRG (329) Anti-Human Rabbit IgG Affinity Purify
Among the diseases which should be distinguished from iNPH (idiopathic normal pressure hydrocephalus) of elderly people showing symptoms such as gait disorder and dementia, there are some neurodegenerative diseases such as Alzheimer's disease, FTLD...
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IL-1β (C) Anti-Rat Rabbit IgG Affinity Purify
The interleukin-1 (IL-1) species represent an important family of biologically active mono nuclear cell-derived proteins which are involved in inflammatory reactions and in immune responses. Two distinct IL-1 species, IL-1αand IL-1β, have been...
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Antibodies
An antibody is an immunoglobulin protein capable of specific combination with an antigen/hapten that has elicited and induced an immune response. Antibodies are produced by B cells in response to presence of antigen/hapten.