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Anti-Human Girdin (Phospho-Y1764) Rabbit IgG (Affinity Purify)

Product Description

Girdin is a new protein playing an important role in the infiltration and metastasis of cancer cells. A new substance of Akt, Girdin (Girders of actin filament) was discovered by a research group led by Takahashi et al., Nagoya University by screening using the yeast two-hybrid method. This elucidated that Girdin has an important role for cell migration downstream of Akt.

It was proven that Girdin is a new actin binding protein and it restructures actin fibers upon being phosphorylated by Akt. It's involved in forming of lamellipodia located at the leading edge of cells and plays an important role for cell migration by functional analysis. It has been suggested that the condition of phosphorylated Girdin is involved in structural alterations in regard to cell migration in vivo or in vitro by current studies using the IBL Girdin antibodies.

List Price: $499.00
QTY
SKU:
28145

Product Description

Girdin is a new protein playing an important role in the infiltration and metastasis of cancer cells. A new substance of Akt, Girdin (Girders of actin filament) was discovered by a research group led by Takahashi et al., Nagoya University by screening using the yeast two-hybrid method. This elucidated that Girdin has an important role for cell migration downstream of Akt.

It was proven that Girdin is a new actin binding protein and it restructures actin fibers upon being phosphorylated by Akt. It's involved in forming of lamellipodia located at the leading edge of cells and plays an important role for cell migration by functional analysis. It has been suggested that the condition of phosphorylated Girdin is involved in structural alterations in regard to cell migration in vivo or in vitro by current studies using the IBL Girdin antibodies.

Other Details

application:
This antibody can be used for; Immunocytochemistry (ICC) in concentration of 0.2 μg/mL Western blotting (W.B.) in concentration of 0.4 ~ 1 μg /mL
Catalog number:
28145
Datasheet:
formulation:
Lyophilized product in PBS containing 1 % BSA and 0.05 % NaN3
immunogen:
Synthetic peptide of the phosphorylated part of Human Girdin (RKTEDT(pY)FISSAG)
notes:
For research use only, not for use in diagnostic procedures.
The datasheet for this product (see above) is intended to serve as an example only. Please refer to the datasheet provided with the antibody for precise details.
purification:
Affinity purified with antigen peptide
size:
50 µg
specificity:
Cross-react with Human Phosphorylated Girdin
storage:
Lyophilized product, 5 years at 2 ~ 8 °C. Solution, 2 years at –20 °C
species:
Human
host:
Rabbit
additional info:

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