Monoclonal Antibodies

Monoclonal antibodies (mAb or moAb) are derived from a single B-cell parent clone and therefore only recognize a single epitope per antigen.

These B-cells are immortalized by fusion with hybridoma cells, allowing for long-term generation of identical monoclonal antibodies.

Monoclonal antibodies specifically detect a particular epitope on the antigen and therefore are less likely than polyclonal antibodies to cross-react with other proteins.

IBL-America offers a wide range of monoclonal antibodies that can be used in the research and development of multiple laboratory testing applications.

Hepatic Sinusoidal Endothelial Cells (SE-1) Anti-Rat Mouse IgG MoAb 1

Among the vascular endothelial cells, hepatic sinusoidal endothelial (HSE) cells are morphologically unique because they have open fenestrations in their cytoplasm and lack basal lamina.

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GRO/CINC-1 (2A9) (N) Anti-Rat Mouse IgG MoAb 1

Cytokine-induced neutrophil chemo attractant 1(CINC-1) was originally purified from media conditioned by IL-1 β stimulated rat kidney epithelioid cells (NRK-52E).

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Galectin-3 (87B5) Anti-Human Mouse IgG MoAb 1

Galectin is widely distributed in nematodes, insects, and porifers, as well as vertebrates, and it has also been found to be present in true fungi. Galectin does not just occur in the cytoplasm, it is also present in the nucleus, on the cell surface, in...

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FAS (14G5) Anti-Human Mouse IgG MoAb 1

Animal fatty acid synthase (FAS) is a homodimer protein, which synthesizes long-chain fatty acids and is rich in liver, brain, breast and lung. However, the precise cellular localization of FAS in human tissue has not been elucidated

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ERK (Clone 5) Anti-Human Mouse IgG MoAb 1

The cell signaling molecules in Mitogen-Activated Protein (MAP) kinase family are playing the central role in the cell response. Extracellular Signal-Regulated Kinase (ERK), c-jun amino-terminal kinase (JNK), and p38 are well known molecules in the...

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Endothelin-B Receptor (8Z11) Anti-Human Mouse IgG MoAb 1

ET-A receptor is ET-1 specific and expressed in lung, aorta, atrium, liver, muscle, cerebral cortex, cerebellum, kidney, adrenal, duodenum, colon and placenta at the mRNA or cDNA level, while ET-B receptor lacks isopeptide specificity and is found in...

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τ/E2 Junction (1A1) Anti-Human Mouse IgG MoAb 1

Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50~70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally

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CRMP-2 (N3E) Anti-Human Mouse IgG MoAb 1

CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis...

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CRMP-2 (C4G) Anti-Human Mouse IgG MoAb 1

CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis...

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COX-2 (13H14) Anti-Human Mouse IgG MoAb 1

Cyclooxygenase (COX) is a membrane bound enzyme responsible for the oxidation of arachidonic acid to Prostaglandin G2 (PGG2) and the subsequent reduction of PGG2 to PHG2.

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ApoE4 (5B5) Anti-Human Mouse IgG MoAb 1

Apolipoprotein E (ApoE) is a structural component of very low-density lipoprotein (VLDL) synthesized by the liver and intestinally synthesized chylomicrons. It is also a constituent of a subclass of high-density lipoproteins (HDLs) involved in...

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Amyloid Beta ( 11-28 ) ( 12B2 ) Aβ Anti-Human Mouse IgG MoAb 1

Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid (Aβ) peptide, a 40 to 43 amino acid...

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