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Etanercept (Enbrel®) ELISA

$1,110.00
SKU:
TM09005
Bulk Pricing:
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ImmunoGuide® Enzyme immunoassay (ELISA) test kit for the determination of free Etanercept (Enbrel®) in serum and plasma.<br><br>

The drug Etanercept (trade name Enbrel®) is a dimeric fusion protein consisting of the extracellular ligand-binding portion of the human 75 kilodalton (p75) tumor necrosis factor receptor (TNFR) linked to the Fc portion of human IgG1. Etanercept binds specifically to human tumor necrosis factor alpha (TNF-α) and blocks its interaction with cell surface TNF receptors. It was possible to show that the surveillance of circulating Etanercept concentration during maintenance therapy represents a direct and/or indirect factor for immunogenicity and some other side effects. In this context, identification of biomarkers for (non-)response and risk factors for adverse drug reactions that might be related to serum concentrations and maintaining the effective concentration of Etanercept in order to potentially avoid some side effects with a reliable method might be beneficial. For research use only, not for use in diagnostic procedures.

Assay Description:
60 min. incubation (RT) + 30 min. (RT) + 15 min. (RT) = 1 hour, 45 min. total incubation time
Catalog number:
TM09005
configuration:
96 Determinations, 12x8 removable strips
controls:
None provided
design:
Enzyme immunoassay (ELISA) technique
FDA Status:
For research use only, not for use in diagnostic procedures
MSDS:
Available upon request
notes:
The protocol for this product (see above) is intended to serve as an example only. Please refer to the Instructions For Use provided with the assay kit for precise details.
Protocol:

Protocol

Sample types:
Serum and plasma
Sample volume:
10 µL
standards:
5 standards, ready to use
Standard range:
0 / 6 - 200 ng/mL
storage:
2 - 8 °C
sensitivity:
5 ng/mL
Species:
Human
Products related:
Etanercept (mAb-based) ELISA
Anti-Etanercept ELISA
Additional info:

Pamphlet