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TNF-α Anti-Rat Rabbit IgG Affinity Purify
TNF-α (Tumor Necrosis Factor alpha) is a 17.5 kDa, 157 amino acid protein that is a potent lymphoid factor, which exerts cytotoxic effects on a wide range of tumor cells and other target cells. TNF-α has been suggested to play a...
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TIMP-1 (T172) Anti-Human Rabbit IgG Affinity Purify
Tissue inhibitor of Metalloprotinase 1 (TIMP-1) is endogenous-specific inhibitor produced simultaneously with matrix metalloproteinase (MMP). TIMP-1 inhibits both active MMP to control degeneration of extracellular matrix (ECM) and conversion of...
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Tie (N1125) Anti-Human Rabbit IgG Affinity Purify
TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...
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Thioredoxin (C) Anti-Human Rabbit IgG Affinity Purify
Thioredoxin is a 12kDa oxidoreductase enzyme containing a dithiol-disulfide active site, and it acts as antioxidants by facilitating the reduction of other proteins by cysteine thiol-disulfide exchange. This redox-regulatory protein thioredoxin has...
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Tau Anti-Human Rabbit IgG Affinity Purify
Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50-70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. It is known that six isoforms of tau protein formed by...
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α-Synuclein (S122) Anti-Human Rabbit IgG Affinity Purify
The pre-synaptic protein, α-synuclein, has been associated with the pathogenesis of several neurodegenerative diseases. These include prevalent conditions such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and the Lewy body variant...
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Syndecan-4 Anti-Human Rabbit IgG Affinity Purify
Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular...
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Anti-Synaptotagmin IV Rabbit IgG Affinity Purify
Synaptotagmin family proteins consist of a single N-terminal transmembrane domain and C-terminal tandem C2 domains (C2A and C2B), which have the ability to bind Ca2+ and phospholipid, and 15 synaptotagmin isoforms have been reported in the mouse and...
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Anti-Smad3L (Ser 208/213 Phosphorylated) Rabbit IgG Affinity Purify
Smads are critical mediators conveying signals from the TGF-β-superfamily members to the nucleus. Activated TGF-β type I receptor (TβRI) and c-Jun N-terminal kinase (JNK) differentially phosphorylate Smad3 to convert two distinctive...
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Anti-Smad3C (Ser 423/425 Phosphorylated) Rabbit IgG Affinity Purify
Smads are critical mediators conveying signals from the TGF-β-superfamily members to the nucleus. Activated TGF-β type I receptor (TβRI) and c-Jun N-terminal kinase (JNK) differentially phosphorylate Smad3 to convert two distinctive...
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Sir2/SIRT1 Anti-Human Rabbit IgG Affinity Purify
Imai et al. have found that S. cerevisiae Sir2p and its higher eukaryotic orthologs are novel nicotinamide adenine dinucleotide (NAD)-dependent histone/protein deacetylases. Sir2 proteins promote longevity in yeast and in C. elegans by silencing rDNA and...
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Septin 7 (C) Anti-Human Rabbit IgG Affinity Purify
A cytoskeletal or scaffold protein family named “septin” has been shown to be involved in diverse phenomena in the living body, including cell division. The term “septin” is derived from “septation,” which means...
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