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Anti-Smad2L/3L (T220/T179 Phosphorylated) (1A1) Mouse IgG MoAb 1
Phosphorylation of signal transduction molecules, Smad2 and Smad3, can be an important information for understanding of various biological functions of transforming growth factor (TGF)-β. TGF-β type I receptor and cyclin-dependent kinases...
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IRF-3 (S386 Phosphorylated) Anti-Human Rabbit IgG Affinity Purify 1
Interferon Regulatory Factor-3 (IRF-3) is the gene coding for a regulatory factor that mediates the action of IL-1, TNFα and LPS. It is reported that IRF-3 controls the production of interferons and chemokines in virus infected cells, by a...
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XIAP Anti-Human Rabbit IgG Affinity Purify 1
IAP (inhibitor of apoptosis protein) is an evolutionarily-conserved inhibitory factor of apoptosis. IAP directly binds to caspase which plays the central role in operation of apoptosis and inhibits it. Human XIAP (X-chromosome-linked inhibitor of...
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VEGF-C(103) Anti-Human Rabbit IgG Affinity Purify 1
The vascular endothelial growth factor family has recently been expanded by the isolation of two new VEGF-related factors, VEGF-B and VEGF-C. The physiological functions of these factors are largely unknown. Recently, it is reported that the cloning and...
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VEGF (V-N) Anti-Rat Rabbit IgG Affinity Purify 1
Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and secreted by a variety of vascularized tissues. It was subsequently found to be...
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VEGF (V-N) Anti-Human Rabbit IgG Affinity Purify 1
Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and secreted by a variety of vascularized tissues. It was subsequently found to be...
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VEGF (V-3) Anti-Human Rabbit IgG Affinity Purify 1
Vascular Endothelial Cell Growth Factor (VEGF) is a homodimeric protein initially purified from media conditioned by normal bovine pituitary folliculo-stellate cells and secreted by a variety of vascularized tissues. It was subsequently found to be...
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TSC1/Hamartin (T1149) Anti-Human Rabbit IgG Affinity Purify 1
TSC1 is a tumor-suppressor gene encoding a protein TSC1/Hamartin of about 130 kDa. Loss of its function causes TSC (tuberous sclerosis complex) or angiomyolipoma in human and in an animal model, TSC1 knockout mouse develops a renal tumor. TSC1/Hamartin,...
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TPO Anti-Human Rabbit IgG Affinity Purify 1
Thrombopoietin (TPO) is produced primarily in the liver and secondarily in the kidneys and bone marrow. It can bind to a receptor (which is the proto-oncogene c-Mpl, a homolog of an envelope protein of the myeloproliferative leukemia virus) on primitive...
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TNF-α Anti-Rat Rabbit IgG Affinity Purify 1
TNF-α (Tumor Necrosis Factor alpha) is a 17.5 kDa, 157 amino acid protein that is a potent lymphoid factor, which exerts cytotoxic effects on a wide range of tumor cells and other target cells. TNF-α has been suggested to play a...
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Tie (N1125) Anti-Human Rabbit IgG Affinity Purify 1
TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...
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α-Synuclein (S122) Anti-Human Rabbit IgG Affinity Purify 1
The pre-synaptic protein, α-synuclein, has been associated with the pathogenesis of several neurodegenerative diseases. These include prevalent conditions such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and the Lewy body variant...
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