Antibodies

An antibody is an immunoglobulin protein capable of specific combination with an antigen/hapten that has elicited and induced an immune response. Antibodies are produced by B cells in response to presence of antigen/hapten.

TSC1/Hamartin (T1149) Anti-Human Rabbit IgG Affinity Purify 1

TSC1 is a tumor-suppressor gene encoding a protein TSC1/Hamartin of about 130 kDa. Loss of its function causes TSC (tuberous sclerosis complex) or angiomyolipoma in human and in an animal model, TSC1 knockout mouse develops a renal tumor. TSC1/Hamartin,...

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TNF-α Anti-Rat Rabbit IgG Affinity Purify 1

TNF-α (Tumor Necrosis Factor alpha) is a 17.5 kDa, 157 amino acid protein that is a potent lymphoid factor, which exerts cytotoxic effects on a wide range of tumor cells and other target cells. TNF-α has been suggested to play a...

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Tie (N1125) Anti-Human Rabbit IgG Affinity Purify 1

TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...

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α-Synuclein (S122) Anti-Human Rabbit IgG Affinity Purify 1

The pre-synaptic protein, α-synuclein, has been associated with the pathogenesis of several neurodegenerative diseases. These include prevalent conditions such as Parkinson's disease (PD), dementia with Lewy bodies (DLB), and the Lewy body variant...

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Syndecan-4 Anti-Human Rabbit IgG Affinity Purify 1

Syndecan, a cell surface proteoglycan, is an integral membrane protein acting as a receptor for the extracellular matrix. The syndecan family of four transmembrane heparan sulfate proteoglycans binds a variety of soluble and insoluble extracellular...

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Sir2/SIRT1 Anti-Human Rabbit IgG Affinity Purify 1

Imai et al. have found that S. cerevisiae Sir2p and its higher eukaryotic orthologs are novel nicotinamide adenine dinucleotide (NAD)-dependent histone/protein deacetylases. Sir2 proteins promote longevity in yeast and in C. elegans by silencing rDNA and...

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Anti-SCF (K236) Rabbit IgG Affinity Purify 1

Stem cell factor (SCF) and its receptor KIT play an important role in various biologic phases, such as hematopoiesis, reproduction, and regeneration.　 Structurally, c-Kit contains five immunoglobulin-like domains extracellularly and a catalytic domain...

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Anti-SCF (K165) Rabbit IgG Affinity Purify 1

Stem cell factor (SCF) and its receptor KIT play an important role in various biologic phases, such as hematopoiesis, reproduction, and regeneration. Structurally, c-Kit contains five immunoglobulin-like domains extracellularly and a catalytic domain...

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Anti-SCF (K089) Rabbit IgG Affinity Purify 1

Stem cell factor (SCF) and its receptor KIT play an important role in various biologic phases, such as hematopoiesis, reproduction, and regeneration.　 Structurally, c-Kit contains five immunoglobulin-like domains extracellularly and a catalytic domain...

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RON (G1385) Anti-Human Rabbit IgG Affinity Purify 1

The c-MET gene encodes the tyrosine kinase p190MET, the receptor for a molecule known as Scatter Factor (SF) or Hepatocyte Growth Factor (HGF). This molecule has biological activities on epithelial sheets, including mitogenesis, cell-cell dissociation,...

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Rictor (R1291) Anti-Human Rabbit IgG Affinity Purify 1

Rictor (rapamycin-insensitive companion of mTOR/ mAVO3) is about 200 kDa and identified as an mTOR-binding protein. Rictor is a factor that constitutes a complex with mLST8 and Sin 1 which is called mTORC2 (mTOR complex 2), and it is contrasted with...

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Rheb (R165) Anti-Human Rabbit IgG Affinity Purify 1

Rheb (ras homolog enriched in brain) is a 20 kDa protein identified as a Ras homolog expressed in the rat hippocampus, but it widely exists in a variety of cells. It is also reported that GTP-binding form is predominant in Rheb, unlike other low...

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