Antibodies

An antibody is an immunoglobulin protein capable of specific combination with an antigen/hapten that has elicited and induced an immune response. Antibodies are produced by B cells in response to presence of antigen/hapten.

dbpA Anti-Human Rabbit IgG Affinity Purify 1

DbpA (DNA Binding protein A) belongs to the Y-box binding protein family that contain a DNA binding domain, called the cold shock domain, of about 80-amino-acid residues. DbpA was identified as the protein binding to the epidermal growth factor receptor...

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Claudin-8 (C) Anti-Mouse Rabbit IgG Affinity Purify 1

Claudin is a transmembrane protein that 4 times goes through the membrane to be formed a gene family and a tight junction molecule that is involved in cell to cell adhesion of epithelial and endothelial cell sheets. It also gets together among several...

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CRMP-2 (Phosphorylated) (3F4) Anti-Human Mouse IgG MoAb 1

CRMP-2 (Collapsin response mediator protein-2) is highly expressed in the developing nervous system and identified as protein involved in Semaphorin 3A (Collapsin-1) intracellular signaling. It is reported that the mutation of unc-33, a Caenorhabditis...

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p16 INK4a (1H4) Anti-Human Mouse IgG MoAb 1

p16INK4a is a cyclin-dependent kinase (CDK) inhibitor, and binds CDK4 and CDK6 and inhibits their kinase activity. It is also called MTS1 and INK4a, and p15INK4b (MTS2), p18INK4c and p19INK4d are other members of the INK4 family. p16INK4a is a tumor...

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Tau (Phosphorylated) (C5) Anti-Human Mouse IgG MoAb 1

Tau protein is a microtubule-associated protein expressed in neuroaxon and has molecular weight of 50 - 70 kDa. Some Alzheimer's patients have sites where tau protein is accumulated abnormally. This antibody reacts with phosphorylated part in amino acid...

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Anti-TP (ATYMPMAB) Mouse IgG MoAb 1

Thymidylate synthase/TS (EC 2.1.1.45), Dihydropyrimidine dehydrogenase/DPD (EC 1.3.1.2), Thymidine phosphorylase/TP (EC 2.4.2.4) and Orotate phosphoribosyl transferase/OPRT (EC 2.4.2.10) are known as key enzymes related to nucleic-acid metabolism within...

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NP95 (mt40) Anti-Human Mouse IgG MoAb 1

Np95 has been originally found as a tumor-specific nuclear antigen of 95kDa in mice. Experiments using B10 strains showed that Np95 is enriched in precancerous cells and is abnormally expressed throughout cell cycle in radiation-induced lymphomatoid...

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Reticulocalbin-1 (TMU-6A1) Anti-Human Mouse IgG MoAb 1

Human Reticulocalbin-1 is a 44kDa protein and belongs to the EF (elongation factor) -hand calcium-binding protein family, and it is known as a luminal protein of endoplasmic reticulum (ER) with the C-terminal HDEL (ER retention signal) sequence. Although...

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Tie-1 (9C1) Anti-Human Mouse IgG MoAb 1

TIE is a new receptor-type tyrosine kinase that was cloned from K562, a chronic myelocytic leukemia cell line. Its molecular weight is 117 kDa and its structure begins with an immunoglobulin-like domain from the extracellular N terminal, continues to 3...

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PDGFRβ (22B1) Anti-Human Mouse IgG MoAb 1

PDGF, a ligand of PDGFR, has 4 isofoms, A-, B-, C- and D-chains, and forms hetero and/or homo dimers, PDGF-AA, -AB, -BB, -CC, -DD. On the other hand, PDGFR has 2 isoforms, α- and β-chains and forms hetero and/or homo dimers,...

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KDR (23B31) Anti-Human Mouse IgG MoAb 1

KDR, alternative name Flk-1 (type 2 receptor), is one of the receptors for VEGFs, important growth factors for vasculogenesis, angiogenesis and lymphangiogenesis. Flt-1 (type 1 receptor) is also known as a VEGF receptor. In particular, it is believed...

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RIG-I (CTD) Anti-Human Rabbit IgG Affinity Purify 1

RIG-I (retinoic acid inducible gene-I) is one of cytoplasmic viral sencers which has a RNA helicase domain and it is believed to recognize virus-derived double-stranded RNA (dsRNA). It is considered that RIG-I normally exist as inactive form in cytoplasm...

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