Nivolumab (Opdivo®) (mAb-based)
- SKU:
- TM09029
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ImmunoGuide® Enzyme immunoassay (ELISA) for the specific determination of free Nivolumab in serum and plasma.<br><br>
The drug Nivolumab (Opdivo®) is a fully human IgG4 monoclonal antibody that binds specifically to programmed death-1 (PD-1), a negative regulatory receptor expressed by activated T and B lymphocytes. Binding of Nivolumab to the PD-1 receptor blocks its interaction with the ligands, PDL1 and PD-L2, thereby attenuating PD-1–mediated inhibition of the immune response, including the anti-tumor immune response.<br><br>
The specificity of this test system is achieved by using a monoclonal antibody named "NY-11C3" for the coating of the microtiter plate.<br><br>
This antibody is specific for Nivolumab only and does not cross react with other PD-1 catchers. For research use only, not for use in diagnostic procedures.
ImmunoGuide® Enzyme immunoassay (ELISA) for the specific determination of free Nivolumab in serum and plasma.<br><br>
The drug Nivolumab (Opdivo®) is a fully human IgG4 monoclonal antibody that binds specifically to programmed death-1 (PD-1), a negative regulatory receptor expressed by activated T and B lymphocytes. Binding of Nivolumab to the PD-1 receptor blocks its interaction with the ligands, PDL1 and PD-L2, thereby attenuating PD-1–mediated inhibition of the immune response, including the anti-tumor immune response.<br><br>
The specificity of this test system is achieved by using a monoclonal antibody named "NY-11C3" for the coating of the microtiter plate.<br><br>
This antibody is specific for Nivolumab only and does not cross react with other PD-1 catchers. For research use only, not for use in diagnostic procedures.