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New Products

 

 

 

 

1. Renin III

2. Chlamydia antigen kit now available

3. ANA detect kit

4. New research products

5. New Oncology products

6. Histochemical Antisera & Peptide Controls

7. Human COX-2 ELISA Kit

 

 

 

8. Amyloid β ELISA Kits

9. Anti-prothrombin ELISA

10. New Anti-Tissue Transglutaminase ELISA Screen

11. Anti-nucleosome antibody ELISA

12. ThromboCombo IgG/IgM ELISA 


 

Renin III

IBL-America now offers Renin III Generation, a radioimmunometric kit for quantitative determination of active Renin in human plasma. Click here for product protocal . Contact IBL-America for more details and pricing. This kit is for non-clinical research only.

 

 

 


 

Histochemical Antisera and Peptide Controls

IBL-America now offers an extensive line of histochemcial antisera and peptide controls. Click here for additional information.

Call us for pricing.

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Human COX-2 ELISA Kit- (96 well) - Catalog # 17186

ELISA kit for Human COX-2 in Cell Lysate. 

TNE or RIPA buffer is recommended for preparing cell lysate.  CHAPS or Sucroce Monolaurate buffer is not recommended. Cross reaction with Human COX-1 is below 0.1%. Use of this assay with serum or plasma is not recommended due to low concentration of COX-2 in these samples.

This kit is for non-clinical research use only.

Contact IBL-America for performance data and sample standard curve.



Amyloid b ELISA Kits

Alzheimer's Disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (Ab), a 40 to 43 amino acid peptide cleaved from amyloid precursor protein by b-secretase and a putative g-secretase. Increased release of the 'longer forms' of Ab peptide, Ab 42 or Ab 43, which have a greater tendency to aggregate than Ab 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alles, or may involve other, still undiscovered, factors, Many researchers theorize that it is this increased release of Ab 42/Ab43 which leads to the abnormal deposition of Ab and the associated neurotoxicity in the brains of affected individuals. It is reported that a distinct Ab peptide, Ab N3(pE), is deposited in senile plaques in a dominant and differential manner as compared with the standard Ab N1 peptide.  Thus, it is very useful for AD research to assay Ab42, Ab43, and AbN3 (pE), respectively.

Call IBL-America for more information.

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Anti-prothrombin ELISA for quantitative detection of antibodies in human plasma and serum.

Anti-phospholipid (aPL) antibodies have been associated with venous and arterial thrombosis as well as recurrent foetal loss.  Patients with these symptoms and high aPL antibody levels are diagnosed as having anti-phospholipid syndrome.  The family of aPL antibodies has recently been expanded to include a heterogeneous group of antibodies whose specificity is directed against phospholipid binding proteins or their complex with phospholipids.

Prothrombin is one such phospholipid binding protein and it exerts a procoagulant activity via a prothrombinase complex.  This then triggers the conversion of fibrinogen to fibrin. 

This anti-prothrombin antibody ELISA is a quantitative assay for the detection of anti-prothrombin antibodies in human plasma and serum.  The kit contains color-coded, ready-to-use reagents and takes just 60 minutes to perform.

This kit is for non-clinical research use only.

Contact IBL-America for more details.

 


Anti-Tissue-Transglutaminase ELISA Screen

Anti-tissue Transglutaminase Screen an indirect solid phase enzyme immunoassay (ELISA) for the simultaneous quantitative measurement of IgG and IgA class autoantibodies against tissue Transglutaminase (tTG) in human serum or plasma. The assay is intended for research use only as an aid in the study of celiac disease and dermatitis herpetiformis.

Click here for details.

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Anti-nucleosome antibody ELISA

Anti-dsDNA and anti-histone antibodies are frequently used as markers of Systemic Lupus Erythematosus (SLE).  However there are indications that a significant fraction of SLE patients have little, if any, anti-dsDNA or anti-histone reactivity but they do have high anti-nucleosome activity.  Anti-nucleosome antibodies are a highly sensitive marker of SLE.  They are almost exclusively found in spontaneous as well as drug-induced lupus, scleroderma and mixed connective tissue diseases.  Indeed, about 85% of SLE patients are found to be anti-nucleosome antibody positive.  Thus, while diagnosing for nucleosome-specific antibodies, clinicians could detect a major potentially pathogenic anti-nuclear antigen population that may be over-looked while testing for anti-dsDNA and anti-histone antibodies only.  In addition, testing for anti-nucleosome antibodies may be most useful for clinicians in differential diagnosis of diseases which very often present overlapping syndromes.This Anti-nucleosome antibody ELISA is a quantitative assay for the detection of antibodies in human plasma and serum.  The kit contains color-coded and ready-to-use reagents.  It is easy to perform and takes just 60 minutes.  The test is also compatible with instrumentation.

Contact IBL-America for additional information!

This kit is for non-clinical research use only.

 


ThromboCombo IgG/IgM ELISA

A new indirect enzyme immunoassay for the simultaneous and differentiating detection of autoantibodies (IgG and/or IgM) that are directed against anionic phospholipids and the cofactor Beta 2-Glycoprotein I.  Altogether 12 different patients profiles can be assessed on one plate.  The strips are coated as follows:

  1. Reference antigen (Calibration)
  2. Beta 2-Glycoprotein I
  3. Cardiolipin
  4. Phosphatidyl Serine
  5. Phosphatidyl Inositol
  6. Phosphatidic Acid
  7. Mixture of all phospholipids
  8. Mixture of all phospholipids, without additional coating with Beta-Glycoprotein I
Click here for protocol and additional information.Assay is presently for research and non-clinical use only.
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